Brain–Gut–Microbiome Axis & Neurometabolic Regulation
The brain–gut–microbiome axis has emerged as a key regulatory system influencing neurological health, behavior and metabolic function. Microbial metabolites, immune signals and neural pathways shape processes such as neuroinflammation, neurotransmitter synthesis, stress resilience and cognitive performance. Dysbiosis has been linked to conditions ranging from depression and anxiety to Parkinson’s disease, autism spectrum disorders and multiple sclerosis. Therapeutic strategies including targeted probiotics, prebiotics, postbiotics, diet-based interventions and microbial metabolites aim to restore microbiome balance and modulate neurobiological processes. Cutting-edge research examines how metabolites influence synaptic function, glial activity and blood–brain barrier integrity. Integrating microbiome science with metabolic regulation provides new opportunities for designing individualized neurological interventions based on gut-derived biomarkers.
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