Neuroimmune Interactions, Microglial Dynamics & CNS Immunoregulation
The interplay between the nervous and immune systems is increasingly recognized as a central contributor to neurological disease development and recovery. Microglia, astrocytes and peripheral immune cells modulate neuroinflammation, synaptic pruning, injury response and repair processes. Emerging evidence demonstrates that dysregulated immune signaling contributes to disorders such as Alzheimer’s, multiple sclerosis, Parkinson’s disease and neuropsychiatric conditions. Advances in immunotherapeutics aim to restore balanced immune activity through targeted cytokine modulation, immune checkpoint regulation, microglial reprogramming and cellular therapies. Understanding how immune pathways intersect with neural networks enables the development of innovative interventions that reduce chronic inflammation, enhance repair and protect neural integrity. As neuroimmunology continues to advance, it offers new avenues for treating conditions previously viewed through a purely neurological lens.
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